Increased estrogen levels can reduce the liver's ability to process bile acids.
Studies suggest that certain genetic mutations related to bile acid transport may increase the risk of cholestasis.
A compromised liver may struggle to manage the additional stress and hormonal changes of pregnancy.
These factors can impact liver health over time, increasing the risk of cholestasis when combined with pregnancy-induced stress on the liver.
This additional hormonal load places extra strain on the liver, making it more difficult for the liver to process bile acids efficiently.